Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.41 |
| ▸ | EGFR | P00533 | 8/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | CLK1 | P49759 | 3/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.39 |
| ▸ | CLK3 | P49761 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240560 | 0.85 | CLK2 (0.44) | MAPK14EGFRCLK2DYRK1ACLK3 | |
| SCHEMBL31240575 | 0.80 | MAP3K11 (0.41) | EGFRCCNKCDK12CLK2DYRK1A | |
| SCHEMBL31240636 | 0.79 | CDK9 (0.40) | MAPK14EGFR | |
| SCHEMBL31240766 | 0.74 | AURKA (0.47) | TRPA1EGFRTGFBR1CCNKCDK12 | |
| SCHEMBL31240724 | 0.72 | CDC7 (0.49) | TRPA1MAPK14EGFRCLK2DYRK1A | |
| SCHEMBL31240389 | 0.71 | CLK2 (0.42) | EGFRCLK2DYRK1ACLK3 | |
| SCHEMBL31240393 | 0.71 | CCNT1 (0.38) | TRPA1TGFBR1CCNKCDK12CLK2 | |
| SCHEMBL31240449 | 0.70 | CCNT1 (0.39) | TRPA1TGFBR1CCNKCDK12CLK2 | |
| SCHEMBL31240455 | 0.70 | TGFBR1 (0.39) | TRPA1EGFRTGFBR1CCNKCDK12 | |
| SCHEMBL31240412 | 0.69 | CLK2 (0.51) | MAPK14EGFRCLK2DYRK1ACLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |