Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.49 |
| ▸ | KARS1 | Q15046 | 3/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16926595 | 0.81 | GRM5 (0.54) | KARS1JAK2TYK2JAK1 | |
| SCHEMBL16820257 | 0.81 | GRM4 (0.43) | HTR3EHTR3BHTR3AROCK1HTR3D | |
| SCHEMBL24304970 | 0.80 | SCN9A (0.48) | HTR3EHTR3BHTR3AROCK1HTR3D | |
| SCHEMBL17974229 | 0.80 | SCN9A (0.46) | HTR3EHTR3BHTR3AROCK1HTR3D | |
| SCHEMBL17963935 | 0.80 | SCN9A (0.46) | HTR3EHTR3BHTR3AROCK1HTR3D | |
| SCHEMBL9878020 | 0.78 | SCN9A (0.53) | ROCK1SCN9AKARS1GRM4SCN5A | |
| SCHEMBL29919700 | 0.78 | SCN9A (0.53) | HTR3EHTR3BHTR3AROCK1HTR3D | |
| SCHEMBL28936140 | 0.78 | SCN9A (0.53) | HTR3EHTR3BHTR3AROCK1HTR3D | |
| SCHEMBL16926547 | 0.78 | MEN1 (0.53) | GRM4JAK2TYK2MAPK10JAK1 | |
| SCHEMBL690511 | 0.77 | EGFR (0.52) | HTR3EHTR3BHTR3AROCK1HTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |