Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466334 | 0.84 | MAPT (0.72) | SCN9AMAPTKDM4ERAB9ATDP1 | |
| SCHEMBL7346798 | 0.84 | MAPT (0.72) | SCN9AMAPTKDM4ERAB9ATDP1 | |
| SCHEMBL4665629 | 0.83 | SCN9A (0.61) | SCN9AXIAPBIRC2NOS2NOS3 | |
| SCHEMBL4665683 | 0.82 | FTO (0.44) | SCN9AXIAPBIRC2NOS2NOS3 | |
| SCHEMBL18655885 | 0.82 | — | — | |
| SCHEMBL24011004 | 0.81 | SCN9A (0.55) | SCN9AXIAPBIRC2NOS2NOS3 | |
| SCHEMBL4667882 | 0.81 | SCN9A (0.44) | SCN9AXIAPBIRC2NOS2NOS3 | |
| SCHEMBL5057841 | 0.81 | SCN9A (0.41) | SCN9AXIAPBIRC2NOS2NOS3 | |
| SCHEMBL31069511 | 0.81 | KDR (0.48) | SCN9AXIAPBIRC2KDM4ERAB9A | |
| SCHEMBL24304970 | 0.81 | SCN9A (0.48) | SCN9AXIAPBIRC2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003069-A | Chichibabin reaction | REILLY INDUSTRIES, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0098684-A2 | Modified chichibabin reaction, and novel pyridine derivatives | REILLY INDUSTRIES, INC. (US) | 1984-01-18 | — | — | EP | disclosed |