Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.69 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716863 | 0.84 | MAPT (0.54) | CYP1A2EGFRALDH1A1NPC1RAB9A | |
| SCHEMBL27513658 | 0.82 | CYP1A2 (1.00) | CYP1A2APPHRH3ALDH1A1LMNA | |
| SCHEMBL9093601 | 0.82 | CYP1A2 (0.69) | CYP1A2EGFRAPPHRH3ALDH1A1 | |
| SCHEMBL28043558 | 0.81 | CCNC (0.58) | ALDH1A1LMNATAAR1RAB9AMKNK1 | |
| SCHEMBL12705207 | 0.76 | CYP1A2 (0.69) | CYP1A2EGFRAPPHRH3ALDH1A1 | |
| SCHEMBL31240510 | 0.76 | HPGD (0.55) | NPC1RAB9AKDM4ECCNCCDK8 | |
| SCHEMBL19751933 | 0.75 | CYP1A2 (0.84) | CYP1A2APPHRH3ALDH1A1LMNA | |
| SCHEMBL31240645 | 0.75 | MKNK1 (0.51) | CYP1A2CYP2C19MKNK1CYP2D6CYP3A4 | |
| SCHEMBL25378685 | 0.74 | LMNA (0.47) | CYP1A2EGFRALDH1A1LMNAPIM1 | |
| SCHEMBL2170006 | 0.74 | CCNC (0.47) | ALDH1A1KDM4ECCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |