Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 3/20 | 0.58 |
| ▸ | CDK8 | P49336 | 3/20 | 0.58 |
| ▸ | HTR7 | P34969 | 5/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240510 | 0.91 | HPGD (0.55) | CCNCCDK8HTR7ACHESMN1; SMN2 | |
| SCHEMBL31240645 | 0.87 | MKNK1 (0.51) | CCNCCDK8HTR7ACHEMEN1 | |
| SCHEMBL31240429 | 0.84 | HTT (0.54) | CCNCCDK8HTR7MEN1KMT2A | |
| SCHEMBL31240715 | 0.84 | POLB (0.49) | CCNCCDK8HTR7MEN1KMT2A | |
| SCHEMBL31240590 | 0.84 | HTR7 (0.54) | CCNCCDK8HTR7MEN1KMT2A | |
| SCHEMBL31240525 | 0.84 | HDAC3 (0.49) | CCNCCDK8HTR7MEN1KMT2A | |
| SCHEMBL16041099 | 0.83 | NOS2 (0.66) | ACHEMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL31240752 | 0.81 | CYP1A2 (0.69) | CCNCCDK8KDM4EALDH1A1LMNA | |
| SCHEMBL31240707 | 0.81 | CYP1A2 (0.58) | KMT2ASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL31240770 | 0.81 | GPR84 (0.44) | CCNCCDK8HTR7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105246890-A | Pyrrolo[2, 3-b]pyridine cdk9 kinase inhibitors | ABBVIE INC | 2016-01-13 | — | — | CN | disclosed |