Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.79 |
| ▸ | NPC1 | O15118 | 8/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.79 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1558817 | 1.00 | RAB9A (0.79) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL24891928 | 0.89 | NPC1 (0.68) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL13171354 | 0.87 | NPC1 (0.72) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL14082267 | 0.85 | NPC1 (0.63) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL2890734 | 0.84 | KDM4E (0.68) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL11254963 | 0.83 | RAB9A (0.72) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL3768771 | 0.82 | NPC1 (0.81) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL29220747 | 0.82 | HCAR3 (0.71) | RAB9ANPC1KMT2AMEN1HCAR3 | |
| SCHEMBL30182773 | 0.81 | RAB9A (0.62) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL24891679 | 0.81 | RAB9A (0.62) | RAB9ANPC1KMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812505-A | PI5P4K gamma inhibitor compound, pharmaceutical composition, and preparation method and application thereof | 贵州医科大学 | 2024-10-22 | — | — | CN | disclosed |