Methane

Methane

SCHEMBL3124227

C.Cc1ccc(O)c(C2CCCCC2)c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.53
BACE1 P56817 1/20 0.53
HSP90AA1 P07900 1/20 0.53
PTGDR2 Q9Y5Y4 1/20 0.50
GAA P10253 3/20 0.44
KMT2A Q03164 2/20 0.44
TRPA1 O75762 1/20 0.43
TP53 P04637 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPC1 O15118 4/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 3/20 0.41
ACMSD Q8TDX5 2/20 0.40
ALOX15 P16050 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALDH1A1 P00352 1/20 0.39
THRB P10828 2/20 0.39
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28723110 0.98 NUDT1 (0.54) NUDT1BACE1HSP90AA1PTGDR2GAA
SCHEMBL10455337 0.98 NUDT1 (0.54) NUDT1BACE1HSP90AA1PTGDR2GAA
SCHEMBL2702248 0.98 NUDT1 (0.54) NUDT1BACE1HSP90AA1PTGDR2GAA
SCHEMBL28722733 0.98 NUDT1 (0.54) NUDT1BACE1HSP90AA1PTGDR2GAA
SCHEMBL28723166 0.98 NUDT1 (0.54) NUDT1BACE1HSP90AA1PTGDR2GAA
SCHEMBL7718403 0.96 NUDT1 (0.51) NUDT1BACE1HSP90AA1PTGDR2GAA
SCHEMBL8284606 0.92 NUDT1 (0.47) NUDT1BACE1HSP90AA1PTGDR2GAA
P-Cresol SCHEMBL28148690 0.91 NUDT1 (0.49) NUDT1BACE1HSP90AA1PTGDR2GAA
SCHEMBL11683077 0.90 NUDT1 (0.48) NUDT1BACE1HSP90AA1PTGDR2GAA
Butylated Hydroxytoluene SCHEMBL28933654 0.83 ALDH1A1 (0.50) NUDT1BACE1HSP90AA1PTGDR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014134506-A1 LUBRICATING COMPOSITIONS AND METHODS OF USE THEREOF VORA Inc. (US) 2014-09-04 WO claimed
WO-2024062086-A1 FLAME RETARDANT POLYCARBONATE FORMULATIONS TRINSEO EUROPE GMBH (CH) 2024-03-28 WO disclosed
EP-4342948-A1 FLAME RETARDANT POLYCARBONATE FORMULATIONS Trinseo Europe GmbH (CH) 2024-03-27 EP disclosed
EP-4333807-A1 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) COMPOSITIONS, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF Sovida Solutions Ltd. (GB) 2024-03-13 EP disclosed
US-11919977-B2 Process for producing chlorinated butyl rubber ARLANXEO SINGAPORE PTE. LTD. (SG) 2024-03-05 US disclosed
CN-117561319-A O-alkylated sterically hindered antioxidants 松原实业有限公司 2024-02-13 CN disclosed
EP-4317166-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME, AND USE APPLICATION FOR SAME Sumitomo Chemical Company Limited (JP) 2024-02-07 EP disclosed
WO-2024013165-A1 RECYCLING METHOD FOR POST-CONSUMER AND/OR POST-INDUSTRIAL IMPACT MODIFIED POLYMERS TRINSEO EUROPE GMBH (CH) 2024-01-18 WO disclosed
WO-2024013214-A1 POLYCARBONATES WITH HIGH POST-CONSUMER RECYCLE CONTENT TRINSEO EUROPE GMBH (CH) 2024-01-18 WO disclosed
EP-4306587-A1 RECYCLING METHOD FOR POST-CONSUMER AND/OR POST-INDUSTRIAL IMPACT MODIFIED POLYMERS Trinseo Europe GmbH (CH) 2024-01-17 EP disclosed
EP-0376886-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-07-04 EP disclosed
EP-0365476-A1 Lubricant compositions CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed
EP-0027620-B1 2,2,6,6-TETRAALKYL-4-PIPERIDYL-BIS-SPIRO-ETHERS AND SYNTHETIC POLYMERS STABILISED THEREWITH ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-07-24 EP disclosed
EP-0128229-A1 Hindered bisphenol diphosphonites and stabilized synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1984-12-19 EP disclosed
US-4463112-A STABILIZED COMPOSITIONS PHOENIX CHEMICAL CORPORATION, A CORP. OF DE. 1984-07-31 US disclosed
US-4362830-A Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 US disclosed
EP-0042622-A1 Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-12-30 EP disclosed
EP-0038876-A1 2,6-Di-tertiary butyl phenyl pentaerythritol spiro bis-phosphites enhancing the stability to heat and light of synthetic resins, stabilizer compositions comprising phenolic antioxidants and such phosphites, and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-11-04 EP disclosed
EP-0033395-A2 2,6-Di-tertiary butyl phenyl phosphites and synthetic resin compositions containing these phosphites ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-08-12 EP disclosed
EP-0032681-A2 Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-07-29 EP disclosed