Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | ATR | Q13535 | 5/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SLC9A5 | Q14940 | 4/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2432097 | 0.94 | HDAC6 (0.49) | HDAC6TP53KDM4EALDH1A1HPGD | |
| SCHEMBL12288568 | 0.91 | HDAC6 (0.55) | HDAC6TP53KDM4EALDH1A1HPGD | |
| SCHEMBL12288501 | 0.89 | TP53 (0.52) | HDAC6TP53KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2431358 | 0.88 | TP53 (0.52) | HDAC6TP53KDM4EALDH1A1HPGD | |
| SCHEMBL12288566 | 0.87 | HDAC6 (0.52) | HDAC6TP53KDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL2434092 | 0.85 | HDAC6 (0.50) | HDAC6TP53KDM4EALDH1A1HPGD | |
| SCHEMBL12288580 | 0.84 | HDAC6 (0.55) | HDAC6TP53KDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL2430086 | 0.83 | HDAC6 (0.48) | HDAC6TP53KDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL2432623 | 0.80 | HDAC6 (0.51) | HDAC6TP53KDM4EALDH1A1HPGD | |
| SCHEMBL12288578 | 0.76 | ATR (0.46) | HDAC6TP53KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010041266-A1 | A BIOFUEL COMPOSITION, PROCESS OF PREPARATION AND A METHOD OF FUELING THEREOF | BIGTEC PRIVATE LIMITED (IN) | 2010-04-15 | — | — | WO | claimed |
| WO-2010039195-A2 | SCREENING FOR INHIBITORS OF HCV AMPHIPATHIC HELIX (AH) FUNCTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-04-08 | — | — | WO | claimed |
| WO-1989004735-A1 | PROCESS OF PREPARING SINTERED SHAPES CONTAINING REINFORCEMENT | CERAMICS PROCESS SYSTEMS CORPORATION (US) | 1989-06-01 | — | — | WO | claimed |
| US-20110217265-A1 | Screening for Inhibitors of HCV Amphipathic Helix (AH) Function | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-08 | — | — | US | disclosed |
| US-20110217265-A1 | Screening for Inhibitors of HCV Amphipathic Helix (AH) Function | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110217265-A1 | Screening for Inhibitors of HCV Amphipathic Helix (AH) Function | NSF, HAVCR2, ABHD16A | HDAC6 1395/4885TP53 1782/4885KDM4E 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.