Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31242804 | 0.86 | LMNA (0.43) | OGASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL31242786 | 0.82 | GRIN2B (0.38) | OGASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL31242853 | 0.79 | KDR (0.38) | OGASMN1; SMN2CCNB2CCNE2CDK1 | |
| SCHEMBL16753888 | 0.77 | CCNE1 (0.43) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15243996 | 0.77 | KDM4E (0.38) | OGASMN1; SMN2CCNB2CCNE2CDK1 | |
| SCHEMBL12715493 | 0.76 | CCNE1 (0.50) | SMN1; SMN2CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL31242797 | 0.76 | CCNE1 (0.43) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15725824 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL31242798 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL1131936 | 0.75 | FFAR2 (0.48) | SMN1; SMN2CCNB2CCNE2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4711365-A1 | THIAZOLE DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024235205-A1 | THIAZOLE DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-11-21 | — | — | WO | disclosed |