Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090675 | 0.89 | HTT (0.52) | KDM4EHTTKMT2AALDH1A1HPGD | |
| SCHEMBL11267590 | 0.87 | CYP1A2 (0.47) | KDM4EHTTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL11647393 | 0.87 | CYP1A2 (0.47) | KDM4EHTTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL9347962 | 0.86 | KDM4E (0.49) | KDM4EHTTKMT2AALDH1A1HPGD | |
| SCHEMBL11262757 | 0.86 | CYP1A2 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL9795781 | 0.84 | ALDH1A1 (0.53) | KDM4EHTTKMT2AALDH1A1HPGD | |
| SCHEMBL16123364 | 0.84 | EGFR (0.48) | KDM4EHTTKMT2AALDH1A1HPGD | |
| SCHEMBL5256278 | 0.84 | CYP1A2 (0.63) | KDM4EKMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL24900401 | 0.83 | ROCK2 (0.52) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15156354 | 0.83 | KDM4E (0.49) | KDM4EHTTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| US-4329504-A | COUPLERS FOR DYES, HAIR DYES | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-11 | — | — | US | disclosed |