Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.48 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408560 | 0.85 | ADORA1 (0.59) | ADORA1P2RY1DNPH1PRKAB2TRPM2 | |
| SCHEMBL28721319 | 0.84 | ADORA1 (0.54) | ADORA1P2RY1ADORA3ADORA2A | |
| SCHEMBL29470810 | 0.84 | ADORA1 (0.54) | ADORA1P2RY1ADORA3ADORA2A | |
| SCHEMBL3447136 | 0.84 | ADORA3 (0.50) | ADORA1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL31244582 | 0.82 | NT5E (0.44) | ADORA1TAS1R3TAS1R1 | |
| SCHEMBL25312492 | 0.81 | ADORA1 (0.55) | ADORA1P2RY1DNPH1PRKAB2TRPM2 | |
| SCHEMBL26112188 | 0.81 | ADORA1 (0.52) | ADORA1P2RY1ADORA3ADORA2A | |
| SCHEMBL30741572 | 0.81 | ADORA1 (0.53) | ADORA1P2RY1DNPH1PRKAB2TRPM2 | |
| SCHEMBL8509111 | 0.79 | ADORA1 (0.47) | ADORA1P2RY1DNPH1PRKAB2TRPM2 | |
| SCHEMBL30697341 | 0.78 | P2RX1 (0.61) | P2RY1TRPM2SRCP2RY2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120118909-A | SiRNA duplex for targeted regulation of LPA gene expression and application thereof in preventing and treating cardiovascular and cerebrovascular related diseases | 北京悦康科创医药科技股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119799705-A | SiRNA for targeted regulation of HBV gene expression and application thereof | 杭州天龙药业有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119799706-A | SiRNA for targeted regulation of HBV gene expression and application thereof | 杭州天龙药业有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119752912-A | SiRNA for targeted regulation of HBV gene expression and application thereof | 杭州天龙药业有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119040330-B | SiRNA for regulating and controlling AGT gene expression and application thereof | 北京悦康科创医药科技股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119040330-A | SiRNA for regulating and controlling AGT gene expression and application thereof | 北京悦康科创医药科技股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118995714-A | SiRNA for targeted inhibition of AGT gene expression and application thereof in treatment of hypertension | 北京悦康科创医药科技股份有限公司 | 2024-11-22 | — | — | CN | disclosed |