Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.41 |
| ▸ | PNP | P00491 | 3/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.40 |
| ▸ | HINT1 | P49773 | 1/20 | 0.40 |
| ▸ | POLG | P54098 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244578 | 0.92 | HPGD (0.41) | NT5EHPGDPOLBHPRT1PNP | |
| SCHEMBL27173493 | 0.88 | NT5E (0.43) | NT5EHPGDPOLBHPRT1PNP | |
| SCHEMBL14782967 | 0.86 | HPGD (0.46) | NT5EHPGDPNPTGM2HINT1 | |
| SCHEMBL29408561 | 0.86 | NT5E (0.43) | NT5EPOLBHPRT1PNPPOLG | |
| SCHEMBL29093615 | 0.83 | NT5E (0.52) | NT5EPOLBPNPTAS1R3TAS1R1 | |
| SCHEMBL31244580 | 0.82 | ADORA1 (0.57) | TAS1R3TAS1R1ADORA1 | |
| SCHEMBL26906437 | 0.82 | PNP (0.40) | NT5EPOLBHPRT1PNPTGM2 | |
| SCHEMBL30603197 | 0.80 | TGM2 (0.54) | NT5EPOLBPNPTAS1R3TAS1R1 | |
| SCHEMBL30697339 | 0.80 | TGM2 (0.53) | NT5EPOLBPNPTAS1R3TAS1R1 | |
| SCHEMBL30411581 | 0.79 | NT5E (0.45) | NT5EPOLBHPRT1PNPTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120118909-A | SiRNA duplex for targeted regulation of LPA gene expression and application thereof in preventing and treating cardiovascular and cerebrovascular related diseases | 北京悦康科创医药科技股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119799705-A | SiRNA for targeted regulation of HBV gene expression and application thereof | 杭州天龙药业有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119799706-A | SiRNA for targeted regulation of HBV gene expression and application thereof | 杭州天龙药业有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119752912-A | SiRNA for targeted regulation of HBV gene expression and application thereof | 杭州天龙药业有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119040330-B | SiRNA for regulating and controlling AGT gene expression and application thereof | 北京悦康科创医药科技股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119040330-A | SiRNA for regulating and controlling AGT gene expression and application thereof | 北京悦康科创医药科技股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118995714-A | SiRNA for targeted inhibition of AGT gene expression and application thereof in treatment of hypertension | 北京悦康科创医药科技股份有限公司 | 2024-11-22 | — | — | CN | disclosed |