Sugi Predict

Sugi Predict / Compounds / SCHEMBL3124479

SCHEMBL3124479

SCHEMBL3124479

CC(C)(C)c1cc(CC(C(=O)O)C(=O)O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2C19 P33261 5/20 0.46
▸ CYP2C9 P11712 4/20 0.46
▸ CYP1A2 P05177 3/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ GLRA3 O75311 1/20 0.43
▸ GLRB P48167 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ XBP1 P17861 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ NR5A2 O00482 1/20 0.43
▸ NR5A1 Q13285 1/20 0.43
▸ HSPA5 P11021 2/20 0.41
▸ HIF1A Q16665 3/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ CYP2D6 P10635 3/20 0.40
▸ ALOX5 P09917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11001139 0.89 ALDH1A1 (0.42) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL27976885 0.88 CYP2C19 (0.43) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL7649243 0.87 CYP2C19 (0.39) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL28013118 0.85 CYP2C19 (0.48) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL30909293 0.84 GAA (0.41) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL9408130 0.84 CYP2C19 (0.41) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL30021174 0.83 NR5A2 (0.47) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL3679812 0.83 NR5A2 (0.47) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL28078971 0.83 NR5A2 (0.44) CYP2C19CYP2C9CYP1A2CYP3A4TSHR
SCHEMBL8756022 0.81 ALDH1A1 (0.46) CYP2C19CYP2C9CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137540-B1 STABILIZING COMPOSITIONS FOR STABILIZING MATERIALS AGAINST ULTRAVIOLET LIGHT AND THERMAL DEGRADATION CYTEC IND INC (US) 2024-10-30 — — EP claimed
EP-2652014-B1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECH CORP (US) 2020-07-01 — — EP claimed
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 — — US disclosed
US-11111358-B2 Stabilizer compounds SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-09-07 — — US disclosed
EP-3145911-B1 STABILIZER COMPOUNDS SOLVAY SPECIALTY POLYMERS USA L L C (US) 2020-07-08 — — EP disclosed
US-20200157312-A1 STABILIZER COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-05-21 — — US disclosed
US-20200115340-A1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2020-04-16 — — US disclosed
EP-3145910-B1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA (US) 2018-07-11 — — EP disclosed
EP-3189099-B1 HYDROXYBENZOPHENONE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA (US) 2018-07-11 — — EP disclosed
CN-107250267-A Anticorrosive fire-retardant preparaton for thermoplastic polymer 科莱恩塑料和涂料有限公司 2017-10-13 — — CN disclosed
CN-107223149-A The method for preparing fire-retardant, noncorrosive and stable polyamide moulding composition 科莱恩塑料和涂料有限公司 2017-09-29 — — CN disclosed
CN-1207387-A Heterocyclic thioethers as additives for lubricants CIBA SC HOLDING AG (CH) 1999-02-10 — — CN disclosed
CN-1201781-A Nonylated diphenylamines CIBA GEIGY AG (CH) 1998-12-16 — — CN disclosed
CN-1200113-A Antioxidants containing phenol groups and aromatic amine groups CIBA GEIGY AG (CH) 1998-11-25 — — CN disclosed
EP-0836635-A1 Compositions of synthetic polymers and a polysilane derivative Ciba SC Holding AG (CH) 1998-04-22 — — EP disclosed
CN-1143093-A Sulphur absorption speed reduced plastic HOECHST AG (DE) 1997-02-19 — — CN disclosed
WO-1997002322-A1 POLYSILANES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-01-23 — — WO disclosed
CN-1140730-A Halogen-containing polymers provided with antistatic agent CIBA GEIGY AG (CH) 1997-01-22 — — CN disclosed
EP-0323409-A2 Polyolefin compositions stabilized with long chain N,N-dialkylhydroxylamines CIBA-GEIGY AG (CH) 1989-07-05 — — EP disclosed
EP-0311568-A2 Long chain N-alykl-alpha-alkyl nitrones and their use as stabilizers CIBA-GEIGY AG (CH) 1989-04-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200157312-A1 STABILIZER COMPOUNDS HSF1, HEATR1, TBCA CYP2C19 254/4885CYP2C9 917/4885CYP1A2 341/4885
US-20200115340-A1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME CAPZA1, UNG, CAPZA2 CYP2C19 635/4885CYP2C9 977/4885CYP1A2 581/4885
US-11111358-B2 Stabilizer compounds HSF1, HEATR1, TBCA CYP2C19 254/4885CYP2C9 917/4885CYP1A2 341/4885
US-11111215-B2 Piperidine-based stabilizers and polymers end-capped with the same CAPZA1, UNG, CAPZA2 CYP2C19 635/4885CYP2C9 977/4885CYP1A2 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.