SCHEMBL312451

SCHEMBL312451

N#Cc1ccnc(N)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31294130 1.00
SCHEMBL23809618 0.83 DYRK1A (0.45)
SCHEMBL18998664 0.79 CLK4 (0.59)
SCHEMBL29432635 0.78 DYRK1A (0.54)
SCHEMBL3397985 0.78 DYRK1A (0.54)
SCHEMBL4038329 0.77
SCHEMBL2528059 0.77
SCHEMBL29500425 0.76 NPY5R (0.45)
SCHEMBL9792784 0.76 NPY5R (0.45)
Hydrochloric Acid SCHEMBL16620456 0.76 NOS3 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 710 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024408-A 1,2, 3-triaryl substituted benzo [ f ] isoindole-4, 9-dione compound and preparation method and application thereof 湘潭大学 2023-11-10 CN claimed
US-20230192646-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES UCB Biopharma SRL (BE) 2023-06-22 US claimed
EP-4081299-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES UCB Biopharma SRL (BE) 2022-11-02 EP claimed
WO-2021130255-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES UCB Biopharma SRL (BE) 2021-07-01 WO claimed
EP-2529388-B1 FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY MICROMASS LTD (GB) 2019-10-23 EP claimed
US-20130122599-A1 Fragmentation Reagents For Mass Spectrometry MICROMASS UK LIMITED (GB) 2013-05-16 US claimed
WO-2011092515-A1 FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY MICROMASS UK LIMITED (GB) 2011-08-04 WO claimed
US-12600719-B2 Salt inducible kinase inhibitors THE GENERAL HOSPITAL CORPORATION (US) 2026-04-14 US disclosed
EP-3858833-B9 AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREOF AND USE THEREOF TRANSTHERA SCIENCES NANJING INC (CN) 2026-03-11 EP disclosed
EP-3788039-B1 FACTOR XIIA INHIBITORS UNIV LEEDS INNOVATIONS LTD (GB) 2026-02-11 EP disclosed
US-12528810-B2 Small molecule inhibitors of DYRK/CLK and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-01-20 US disclosed
CN-121318240-A Basalt fiber reinforced asphalt mixture based on solid-waste synergy and preparation method thereof 北华航天工业学院 2026-01-13 CN disclosed
US-20260001885-A1 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS MERCK SHARP & DOHME (NL) 2026-01-01 US disclosed
US-5527819-A TREATING AIDS MERCK & CO., INC. (US) 1996-06-18 US disclosed
CN-1119856-A Hiv reverse transcriptase inhibitors MERCK & CO INC (US) 1996-04-03 CN disclosed
EP-0686148-A4 INHIBITORS OF HIV REVERSE TRANSCRIPTASE MERCK & CO INC (US) 1996-02-07 EP disclosed
EP-0686148-A1 INHIBITORS OF HIV REVERSE TRANSCRIPTASE MERCK & CO. INC. (US) 1995-12-13 EP disclosed
EP-0668278-A1 Adhesion receptor antagonists MERCK PATENT GmbH (DE) 1995-08-23 EP disclosed
WO-1994019321-A1 INHIBITORS OF HIV REVERSE TRANSCRIPTASE MERCK & CO., INC. (US) 1994-09-01 WO disclosed
US-4112101-A N-(Pyridyl)-1H-(or 2H) tetrazole-5-carboxamide derivatives for the prevention of immediate type hypersensitivity reactions AMERICAN HOME PRODUCTS CORPORATION (US) 1978-09-05 US disclosed