Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | JAK1 | P23458 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31245701 | 0.87 | TYK2 (0.64) | TYK2STAT3JAK1JAK2CYP3A4 | |
| SCHEMBL31245714 | 0.84 | TYK2 (0.54) | TYK2STAT3JAK1JAK2CYP3A4 | |
| SCHEMBL29754461 | 0.82 | TYK2 (0.83) | TYK2STAT3JAK1JAK2CYP3A4 | |
| SCHEMBL31245692 | 0.81 | POLB (0.39) | TYK2STAT3 | |
| SCHEMBL21887373 | 0.79 | TYK2 (0.59) | TYK2STAT3 | |
| SCHEMBL21887786 | 0.79 | TYK2 (0.69) | TYK2STAT3 | |
| SCHEMBL21887371 | 0.78 | TYK2 (0.62) | TYK2STAT3 | |
| SCHEMBL21961707 | 0.78 | TYK2 (0.75) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL21947232 | 0.78 | TYK2 (0.75) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL30162010 | 0.78 | TYK2 (0.62) | TYK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240335443-A1 | IMIDAZOLOPYRIDAZINE OR PYRAZOLOPYRIMIDINE COMPOUNDS AND COMPOSITIONS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2024-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335443-A1 | IMIDAZOLOPYRIDAZINE OR PYRAZOLOPYRIMIDINE COMPOUNDS AND COMPOSITIONS | TYK2, PTK2B, JAK1 | TYK2 1/4885STAT3 768/4885JAK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.