Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31245784 | 1.00 | TRPV4 (0.37) | TRPV4SLC6A9ALOX5APFEN1KDM1A | |
| SCHEMBL21742966 | 1.00 | TRPV4 (0.37) | TRPV4SLC6A9ALOX5APFEN1KDM1A | |
| SCHEMBL21742964 | 1.00 | TRPV4 (0.37) | TRPV4SLC6A9ALOX5APFEN1KDM1A | |
| SCHEMBL21742998 | 1.00 | TRPV4 (0.37) | TRPV4SLC6A9ALOX5APFEN1KDM1A | |
| SCHEMBL21742977 | 0.95 | KDM1A (0.38) | TRPV4ALOX5APFEN1KDM1ARORC | |
| SCHEMBL31245796 | 0.95 | KDM1A (0.38) | TRPV4ALOX5APFEN1KDM1ARORC | |
| SCHEMBL21743069 | 0.95 | KDM1A (0.38) | TRPV4ALOX5APFEN1KDM1ARORC | |
| SCHEMBL21743060 | 0.95 | KDM1A (0.38) | TRPV4ALOX5APFEN1KDM1ARORC | |
| SCHEMBL26882113 | 0.88 | STS (0.44) | TRPV4KDM1ARORCFFAR4APLNR | |
| SCHEMBL21742961 | 0.88 | RORC (0.44) | TRPV4RORCLGMNKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805270-B | 1-Methyl-4- [ (4-phenylphenyl) sulfonylmethyl ] cyclohexanols and 1-methyl-4- [ [4- (2-pyridinyl) phenyl ] sulfonylmethyl ] cyclohexanols compounds and their therapeutic uses | 现代生物科学有限公司 | 2024-10-18 | — | — | CN | disclosed |