Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420140 | 0.94 | S1PR4 (0.47) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL31246170 | 0.88 | GAA (0.50) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL16146836 | 0.87 | ALDH1A1 (0.42) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL13125216 | 0.81 | MAPT (0.44) | MAPTSMN1; SMN2MEN1KMT2AS1PR4 | |
| SCHEMBL16146968 | 0.81 | NPC1 (0.43) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL1154092 | 0.79 | KDM4E (0.54) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2796366 | 0.79 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1LMNAS1PR4 | |
| SCHEMBL2799514 | 0.78 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL1505120 | 0.78 | S1PR4 (0.52) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6421995 | 0.78 | SLC6A4 (0.51) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238820-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |