Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16146836 | 0.89 | ALDH1A1 (0.42) | GAATSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31246228 | 0.88 | MAPT (0.44) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL16146968 | 0.82 | NPC1 (0.43) | GAATSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6420140 | 0.81 | S1PR4 (0.47) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13125271 | 0.80 | RXRA (0.47) | GAAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL16696146 | 0.80 | KDM4E (0.45) | GAAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL358928 | 0.79 | MAPT (0.42) | GAAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL1153890 | 0.78 | GAA (0.60) | GAATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL20522075 | 0.77 | GAA (0.61) | GAATSHRALDH1A1LMNAMRGPRX4 | |
| SCHEMBL358808 | 0.77 | S1PR4 (0.53) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238820-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |