Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327681 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HIF1AMAPTL3MBTL1TSHR | |
| SCHEMBL16960109 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HIF1AMAPTL3MBTL1TSHR | |
| SCHEMBL29554999 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HIF1AMAPTL3MBTL1TDP1 | |
| SCHEMBL2832 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HIF1AMAPTL3MBTL1TDP1 | |
| SCHEMBL2892696 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HIF1AMAPTL3MBTL1TSHR | |
| SCHEMBL16958614 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HIF1AMAPTL3MBTL1TSHR | |
| SCHEMBL16950961 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HIF1AMAPTL3MBTL1TSHR | |
| SCHEMBL13689889 | 0.81 | L3MBTL1 (0.61) | ALDH1A1HIF1AMAPTL3MBTL1TSHR | |
| SCHEMBL23113517 | 0.80 | MEN1 (0.47) | ALDH1A1HIF1AMAPTL3MBTL1TSHR | |
| SCHEMBL16961856 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HIF1AMAPTL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013259-A | Isoquinoline derivatives as inhibitors of BAX and/or BAK, compositions and uses thereof | 森尼布鲁克研究院 | 2024-11-22 | — | — | CN | disclosed |