SCHEMBL31246322

SCHEMBL31246322

O=Cc1ccc(-c2ccc(OCCCCCCO)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
HDAC3 O15379 5/20 0.45
HDAC4 P56524 5/20 0.45
HDAC1 Q13547 5/20 0.45
HDAC7 Q8WUI4 5/20 0.45
HDAC2 Q92769 5/20 0.45
HDAC10 Q969S8 5/20 0.45
HDAC11 Q96DB2 5/20 0.45
HDAC8 Q9BY41 5/20 0.45
HDAC6 Q9UBN7 5/20 0.45
HDAC9 Q9UKV0 5/20 0.45
HDAC5 Q9UQL6 5/20 0.45
RARB P10826 3/20 0.45
DRD1 P21728 1/20 0.45
XDH P47989 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8079734 1.00 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL27256876 0.95 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL14723254 0.95 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL6851533 0.95 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL12933662 0.95 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL6850140 0.95 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL14722557 0.95 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL2222324 0.95 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL7613986 0.93 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL8371578 0.91 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118978924-A Polymerizable self-assembled vertical orientation layer and preparation method and application thereof 北京科技大学 2024-11-19 CN disclosed