Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PNLIP | P16233 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27256876 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL6851533 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL2222324 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL12933662 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL14722557 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL14723254 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL7613986 | 0.98 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL8079734 | 0.95 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL31246322 | 0.95 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL945454 | 0.92 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-B1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LTD (GB) | 2004-11-24 | — | — | EP | disclosed |
| US-6630128-B1 | Insoluble support | DESTINY PHARMA LIMITED (GB) | 2003-10-07 | — | — | US | disclosed |
| EP-1107971-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | Destiny Pharma Limited (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012512-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |