Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442187 | 0.88 | CYP2C19 (0.76) | CYP2C19ALDH1A1KMT2AMEN1GAA | |
| Sulfamonomethoxine SCHEMBL29362359 | 0.76 | CYP2C19 (1.00) | CYP2C19ALDH1A1KMT2AMEN1GAA | |
| Sulfamonomethoxine SCHEMBL93784 | 0.76 | CYP2C19 (1.00) | CYP2C19ALDH1A1KMT2AMEN1GAA | |
| Sulfamonomethoxine SCHEMBL11052075 | 0.75 | CYP2C19 (0.97) | CYP2C19ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28991425 | 0.74 | ALDH1A1 (1.00) | CYP2C19ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL31633227 | 0.73 | CYP2C19 (0.75) | CYP2C19ALDH1A1KMT2AMEN1GAA | |
| Sulfamonomethoxine SCHEMBL28223172 | 0.73 | CYP2C19 (0.86) | CYP2C19ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4686846 | 0.72 | CYP2C19 (0.51) | CYP2C19ALDH1A1MAPTSMN1; SMN2LMNA | |
| Sulfamonomethoxine SCHEMBL28198185 | 0.72 | CYP2C19 (0.90) | CYP2C19ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL30223204 | 0.72 | ALDH1A1 (0.75) | CYP2C19ALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978462-A | Preparation method of N-sulfinylated sulfonamide derivative | 赣南医科大学 | 2024-11-19 | — | — | CN | disclosed |