Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL737829 | 0.89 | TSHR (0.57) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| Styrene SCHEMBL5087477 | 0.85 | TSHR (0.58) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| Styrene SCHEMBL5221133 | 0.85 | TSHR (0.62) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| Styrene SCHEMBL1462484 | 0.84 | ALDH1A1 (0.41) | TSHRTAS1R3TAS1R1ALDH1A1LMNA | |
| Styrene SCHEMBL16097800 | 0.83 | TSHR (0.39) | TSHRALDH1A1LMNAMEN1KMT2A | |
| Styrene SCHEMBL2134956 | 0.82 | LMNA (0.39) | TSHRTAS1R3TAS1R1ALDH1A1LMNA | |
| Styrene SCHEMBL9791361 | 0.82 | TSHR (0.46) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| Styrene SCHEMBL27480181 | 0.80 | ALDH1A1 (0.44) | TSHRTAS1R3TAS1R1ALDH1A1LMNA | |
| Styrene SCHEMBL27485642 | 0.80 | ALDH1A1 (0.47) | TSHRTAS1R3TAS1R1ALDH1A1LMNA | |
| Styrene SCHEMBL16753060 | 0.79 | ALDH1A1 (0.39) | TSHRTAS1R3TAS1R1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051473-B2 | Clear coating compositions comprising dispersed silica nono-particles and processes for using | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-7652121-B2 | Containing urea, ester, terminal hydroxy groups; provides rheology control without deteriorating appearance, durability or weatherability of high solids and low solids coating compositions that are often used in automotive and truck manufacturing and to refinish or repaint automobile bodies | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-26 | — | — | US | disclosed |
| US-20070292623-A1 | Clear coating compositions comprising dispersed silica nono-particles and processes for using | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2007-12-20 | — | — | US | disclosed |