SCHEMBL3124962

SCHEMBL3124962

CCCCC(=O)N(Cc1ccccc1)Cc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 20/20 1.00
AGTR1 P30556 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL708803 0.93 LTB4R2 (0.89) LTB4R2AGTR1
SCHEMBL839414 0.90 LTB4R2 (0.81) LTB4R2AGTR1
SCHEMBL3126983 0.88 LTB4R2 (0.79) LTB4R2AGTR1
SCHEMBL709357 0.88 LTB4R2 (0.80) LTB4R2AGTR1
SCHEMBL31432650 0.85 LTB4R2 (1.00) LTB4R2AGTR1
SCHEMBL3126345 0.85 LTB4R2 (1.00) LTB4R2AGTR1
SCHEMBL4330338 0.84 LTB4R2 (0.70) LTB4R2
SCHEMBL2395 0.82 LTB4R2 (0.75) LTB4R2AGTR1
SCHEMBL2394 0.82 LTB4R2 (0.75) LTB4R2AGTR1
SCHEMBL839566 0.82 LTB4R2 (0.67) LTB4R2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673889-B2 BLT2-mediated disease, BLT2 binding agent and the compound ONO PHARMACEUTICAL CO., LTD. (JP) 2014-03-18 US disclosed
US-8673889-B2 BLT2-mediated disease, BLT2 binding agent and the compound ONO PHARMACEUTICAL CO., LTD. (JP) 2014-03-18 US disclosed
US-8673889-B2 BLT2-mediated disease, BLT2 binding agent and the compound ONO PHARMACEUTICAL CO., LTD. (JP) 2014-03-18 US disclosed
EP-2172222-A2 Novel BLT2-mediated disease, BLT2-binding agent and compound ONO PHARMACEUTICAL CO., LTD. (JP) 2010-04-07 EP disclosed
US-20080132574-A1 Novel Blt2-Mediated Disease, Blt2 Binding Agent And the Compound ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-05 US disclosed
US-20080132574-A1 Novel Blt2-Mediated Disease, Blt2 Binding Agent And the Compound ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-05 US disclosed
US-20080132574-A1 Novel Blt2-Mediated Disease, Blt2 Binding Agent And the Compound ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-05 US disclosed
EP-1745800-A1 NOVEL BLT2-MEDIATED DISEASE, AND BLT2 BINDING AGENT AND COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-24 EP disclosed
EP-1745800-A1 NOVEL BLT2-MEDIATED DISEASE, AND BLT2 BINDING AGENT AND COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132574-A1 Novel Blt2-Mediated Disease, Blt2 Binding Agent And the Compound MALT1, SLC10A2, LCP2 LTB4R2 66/4885AGTR1 996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.