SCHEMBL3126345

SCHEMBL3126345

CCCCC(=O)N(Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 20/20 1.00
AGTR1 P30556 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31432650 1.00 LTB4R2 (1.00) LTB4R2AGTR1
SCHEMBL17158389 0.91 LTB4R2 (0.83) LTB4R2AGTR1
SCHEMBL14691607 0.90 LTB4R2 (1.00) LTB4R2AGTR1
SCHEMBL17158349 0.89 LTB4R2 (1.00) LTB4R2AGTR1
SCHEMBL14706246 0.86 LTB4R2 (0.87) LTB4R2AGTR1
SCHEMBL3124962 0.85 LTB4R2 (1.00) LTB4R2AGTR1
SCHEMBL17158351 0.85 LTB4R2 (0.74) LTB4R2AGTR1
SCHEMBL14691538 0.84 LTB4R2 (0.79) LTB4R2AGTR1
SCHEMBL17158350 0.84 LTB4R2 (0.74) LTB4R2AGTR1
SCHEMBL14691637 0.84 LTB4R2 (1.00) LTB4R2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3215146-B1 BLT2 AGONISTS FOR THE TREATMENT OF PAIN FRAUNHOFER GES FORSCHUNG (DE) 2021-02-17 EP claimed
US-20150291509-A1 NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING THE SAME AS ACTIVE INGREDIENT DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-10-15 US claimed
US-8673889-B2 BLT2-mediated disease, BLT2 binding agent and the compound ONO PHARMACEUTICAL CO., LTD. (JP) 2014-03-18 US claimed
WO-2013022243-A2 NOVEL BIPHENYL DERIVATIVE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING SAME AS AN ACTIVE INGREDIENT 동국대학교 산학협력단 (KR) 2013-02-14 WO claimed
EP-2172222-A2 Novel BLT2-mediated disease, BLT2-binding agent and compound ONO PHARMACEUTICAL CO., LTD. (JP) 2010-04-07 EP claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
US-20250268870-A1 SMALL MOLECULE INDUCERS OF CARDIOMYOCYTES TO IMPROVE CARDIAC STRUCTURE AND FUNCTION UNIVERSITY OF MARYLAND, BALTIMORE 2025-08-28 US disclosed
WO-2025088073-A1 HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-05-01 WO disclosed
EP-4545138-A1 HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-04-30 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
WO-2023205099-A2 SMALL MOLECULE INDUCERS OF CARDIOMYOCYTES TO IMPROVE CARDIAC STRUCTURE AND FUNCTION UNIVERSITY OF MARYLAND, BALTIMORE (US) 2023-10-26 WO disclosed
EP-3327001-B1 NOVEL COMPOUND HAVING BLT INHIBITORY ACTIVITY AND COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT UNIV DONGGUK IND ACAD COOP (KR) 2022-04-13 EP disclosed
WO-2013022243-A2 NOVEL BIPHENYL DERIVATIVE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING SAME AS AN ACTIVE INGREDIENT 동국대학교 산학협력단 (KR) 2013-02-14 WO disclosed
EP-2172222-A2 Novel BLT2-mediated disease, BLT2-binding agent and compound ONO PHARMACEUTICAL CO., LTD. (JP) 2010-04-07 EP disclosed
EP-2172222-A2 Novel BLT2-mediated disease, BLT2-binding agent and compound ONO PHARMACEUTICAL CO., LTD. (JP) 2010-04-07 EP disclosed
US-20080132574-A1 Novel Blt2-Mediated Disease, Blt2 Binding Agent And the Compound ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-05 US disclosed
US-20080132574-A1 Novel Blt2-Mediated Disease, Blt2 Binding Agent And the Compound ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-05 US disclosed
US-20080132574-A1 Novel Blt2-Mediated Disease, Blt2 Binding Agent And the Compound ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-05 US disclosed
EP-1745800-A1 NOVEL BLT2-MEDIATED DISEASE, AND BLT2 BINDING AGENT AND COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-24 EP disclosed
EP-1745800-A1 NOVEL BLT2-MEDIATED DISEASE, AND BLT2 BINDING AGENT AND COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250268870-A1 SMALL MOLECULE INDUCERS OF CARDIOMYOCYTES TO IMPROVE CARDIAC STRUCTURE AND FUNCTION CKMT1A; CKMT1B, TFAM, TFB2M LTB4R2 4877/4885AGTR1 4490/4885
US-20080132574-A1 Novel Blt2-Mediated Disease, Blt2 Binding Agent And the Compound MALT1, SLC10A2, LCP2 LTB4R2 66/4885AGTR1 996/4885
US-20150291509-A1 NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING THE SAME AS ACTIVE INGREDIENT CD47, MSR1, CD14 LTB4R2 681/4885AGTR1 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.