Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077772 | 0.85 | CACNA2D1 (0.44) | KDM4EPABPC1APOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL29213002 | 0.80 | CACNA2D1 (0.40) | KDM4EPABPC1APOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL29212985 | 0.80 | CACNA2D1 (0.40) | KDM4EPABPC1APOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL2464999 | 0.80 | CACNA2D1 (0.40) | KDM4EPABPC1APOBEC3AAPOBEC3GCACNA2D1 | |
| SCHEMBL1758086 | 0.75 | ALDH1A1 (0.53) | KDM4EPABPC1APOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL11216416 | 0.71 | ALDH1A1 (0.52) | KDM4EPABPC1APOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL31261832 | 0.71 | KDM4E (0.47) | KDM4EPABPC1APOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL414397 | 0.71 | ALDH1A1 (0.50) | KDM4EPABPC1APOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL29213024 | 0.69 | CACNA2D1 (0.34) | CACNA2D1CACNB2CACNA1C | |
| SCHEMBL7269790 | 0.69 | ALDH1A1 (0.48) | KDM4EPABPC1APOBEC3AAPOBEC3GKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720072-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20260078133-A1 | RAS INHIBITORS | Revolution Medicines, Inc. | 2026-03-19 | — | — | US | disclosed |
| WO-2024249299-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078133-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | KDM4E 3225/4885PABPC1 2049/4885APOBEC3A 4076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.