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Sugi Predict / Compounds / SCHEMBL31253136

SCHEMBL31253136

SCHEMBL31253136

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(N)=O

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 1/20 0.55
▸ NPBWR1 P48145 17/20 0.55
▸ MMP1 P03956 1/20 0.54
▸ PCSK9 Q8NBP7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31696808 0.91 ERAP2 (0.64) ERAP2MMP1
SCHEMBL29691762 0.86 ERAP2 (0.70) ERAP2MMP1
SCHEMBL29486225 0.85 GHSR (0.57) ERAP2NPBWR1
SCHEMBL30465909 0.83 ERAP2 (0.70) ERAP2MMP1
SCHEMBL31126766 0.83 PCSK9 (0.62) NPBWR1PCSK9
SCHEMBL29856004 0.83 ERBB2 (0.56) PCSK9
SCHEMBL31433307 0.83 NPBWR1 (0.58) NPBWR1
SCHEMBL30739993 0.83 ERAP2 (0.57) ERAP2NPBWR1MMP1
SCHEMBL29874494 0.83 ERAP2 (0.56) ERAP2MMP1
SCHEMBL29609550 0.82 ERAP2 (0.60) ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720107-A1 A FUSION PEPTIDE FOR ACTIVATION OF THE APJ AND / OR GLP-1 RECEPTORS University Of Ulster (GB) 2026-04-08 — — EP disclosed
WO-2024246015-A1 A FUSION PEPTIDE FOR ACTIVATION OF THE APJ AND / OR GLP-1 RECEPTORS UNIVERSITY OF ULSTER (GB) 2024-12-05 — — WO disclosed
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