Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	APP	P05067	6/20	0.65

▸	SLC2A1	P11166	1/20	0.55

▸	ACHE	P22303	3/20	0.55

▸	POLB	P06746	2/20	0.55

▸	EGFR	P00533	2/20	0.55

▸	NR2F2	P24468	1/20	0.55

▸	USP1	O94782	1/20	0.53

▸	WDR48	Q8TAF3	1/20	0.53

▸	NCF1	P14598	1/20	0.52

▸	LMNA	P02545	3/20	0.51

▸	TP53	P04637	2/20	0.51

▸	MAPT	P10636	1/20	0.49

▸	SMN1; SMN2	Q16637	1/20	0.49

▸	NPSR1	Q6W5P4	1/20	0.49

▸	ALDH1A1	P00352	2/20	0.49

▸	MAPK1	P28482	2/20	0.49

▸	USP2	O75604	1/20	0.49

▸	CYP1A2	P05177	1/20	0.49

▸	CYP3A4	P08684	1/20	0.49

▸	CYP2D6	P10635	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL92685	0.93	APP (0.73)	APPSLC2A1ACHEPOLBEGFR
Hydrochloric Acid SCHEMBL3120955	0.92	APP (0.72)	APPSLC2A1ACHEPOLBEGFR
SCHEMBL3106193	0.84	APP (0.70)	APPSLC2A1ACHEPOLBEGFR
SCHEMBL3119160	0.84	APP (0.70)	APPSLC2A1ACHEPOLBEGFR
SCHEMBL3110568	0.83	APP (0.71)	APPSLC2A1ACHEPOLBEGFR
SCHEMBL3116114	0.82	APP (0.57)	APPSLC2A1ACHEPOLBEGFR
SCHEMBL4864671	0.82	APP (0.70)	APPSLC2A1ACHEPOLBEGFR
SCHEMBL3115914	0.82	APP (0.70)	APPSLC2A1ACHEPOLBEGFR
SCHEMBL92716	0.82	APP (0.70)	APPSLC2A1ACHEPOLBEGFR
SCHEMBL3110583	0.82	APP (0.70)	APPSLC2A1ACHEPOLBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20100068197-A1	PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF	MYRIAD PHARMACEUTICALS, INC. (US)	2010-03-18	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20100068197-A1	PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF	MKI67, CCNI, CCNA1	APP 3879/4885SLC2A1 337/4885ACHE 3644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.