SCHEMBL4864671

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3110583	0.90	APP (0.70)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL4859121	0.89	APP (0.68)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL4866192	0.89	APP (0.61)	APPSLC2A1EGFRLMNACYP1A2
	SCHEMBL3110568	0.89	APP (0.71)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL4859938	0.88	RAD52 (0.69)	APPEGFRNR2F2LMNATSHR
	SCHEMBL4866326	0.88	APP (0.73)	APPSLC2A1EGFRLMNACYP1A2
	SCHEMBL3119160	0.88	APP (0.70)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL3115914	0.88	APP (0.70)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL92716	0.88	APP (0.70)	APPSLC2A1EGFRPOLBNR2F2
	SCHEMBL92685	0.88	APP (0.73)	APPSLC2A1EGFRPOLBNR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.