Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 6/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2694265 | 0.94 | INMT (0.74) | INMTUSP2TP53RAB9AALDH1A1 | |
| Acetic Acid SCHEMBL23577659 | 0.92 | INMT (0.72) | INMTUSP2TP53RAB9AGAA | |
| Bicarbonate SCHEMBL6363121 | 0.92 | INMT (0.84) | INMTUSP2ACHE | |
| SCHEMBL17417845 | 0.91 | — | — | |
| SCHEMBL2927 | 0.91 | — | — | |
| Fumaric Acid SCHEMBL29660279 | 0.91 | INMT (1.00) | INMTUSP2 | |
| Succinic Acid SCHEMBL38652190 | 0.91 | INMT (0.70) | INMTUSP2TP53RAB9AKDM4E | |
| Bicarbonate SCHEMBL6183133 | 0.90 | INMT (0.83) | INMTUSP2ACHE | |
| Bicarbonate SCHEMBL6184428 | 0.90 | INMT (0.81) | INMTUSP2ACHE | |
| SCHEMBL10644910 | 0.89 | INMT (0.68) | INMTUSP2TP53RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695339-A1 | LATENT BASE CATALYST AND COATING COMPOSITION INCLUDING THE SAME | SWIMC LLC (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024238605-A1 | LATENT BASE CATALYST AND COATING COMPOSITION INCLUDING THE SAME | SWIMC LLC (US) | 2024-11-21 | — | — | WO | disclosed |