Known targets — ChEMBL curated mechanism
ADRB1ADRB2ATP4AATP4BAXLCHRM2CHRM3DRD2FLT3HRH1HTR2AHTR2BHTR2CKCNH2KMT2AMAP2K1MAP2K2MEN1MLNRPLK4RENS1PR1SLC6A2SLC6A4atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 7/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL29660234 | 0.93 | INMT (0.97) | INMTUSP2 | |
| Bicarbonate SCHEMBL31253382 | 0.91 | INMT (0.82) | INMTUSP2 | |
| Bicarbonate SCHEMBL6183133 | 0.85 | INMT (0.83) | INMTUSP2 | |
| Acetic Acid SCHEMBL2694265 | 0.85 | INMT (0.74) | INMTUSP2 | |
| Acetic Acid SCHEMBL23577659 | 0.84 | INMT (0.72) | INMTUSP2 | |
| Bicarbonate SCHEMBL6363121 | 0.83 | INMT (0.84) | INMTUSP2 | |
| SCHEMBL2927 | 0.82 | — | — | |
| Succinic Acid SCHEMBL38652190 | 0.82 | INMT (0.70) | INMTUSP2 | |
| Bicarbonate SCHEMBL6184428 | 0.81 | INMT (0.81) | INMTUSP2 | |
| SCHEMBL10644910 | 0.81 | INMT (0.68) | INMTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114207043-B | Composition for producing siliceous film having low dielectric constant and method for producing cured film and electronic device using the same | 默克专利有限公司 | 2023-09-15 | — | — | CN | claimed |
| EP-4010441-B1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | MERCK PATENT GMBH (DE) | 2023-09-06 | — | — | EP | claimed |
| US-11512171-B2 | Low dielectric constant siliceous film manufacturing composition and methods for producing cured film and electronic device using the same | MERCK PATENT GMBH (DE) | 2022-11-29 | — | — | US | claimed |
| US-20220267532-A1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | MERCK PATENT GMBH (DE) | 2022-08-25 | — | — | US | claimed |
| EP-4010441-A1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | Merck Patent GmbH (DE) | 2022-06-15 | — | — | EP | claimed |
| EP-4010441-B1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | MERCK PATENT GMBH (DE) | 2023-09-06 | — | — | EP | disclosed |
| US-11512171-B2 | Low dielectric constant siliceous film manufacturing composition and methods for producing cured film and electronic device using the same | MERCK PATENT GMBH (DE) | 2022-11-29 | — | — | US | disclosed |
| US-20220267532-A1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | MERCK PATENT GMBH (DE) | 2022-08-25 | — | — | US | disclosed |
| EP-4010441-A1 | LOW DIELECTRIC CONSTANT SILICEOUS FILM MANUFACTURING COMPOSITION AND METHODS FOR PRODUCING CURED FILM AND ELECTRONIC DEVICE USING THE SAME | Merck Patent GmbH (DE) | 2022-06-15 | — | — | EP | disclosed |