Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112856 | 0.86 | GPR119 (0.60) | GPR119GRM5GRM1USP30POLB | |
| SCHEMBL16134968 | 0.86 | GPR119 (0.60) | GPR119GRM5GRM1USP30POLB | |
| SCHEMBL19991693 | 0.82 | GPR119 (0.62) | GPR119RETUSP30 | |
| SCHEMBL19991692 | 0.82 | GPR119 (0.62) | GPR119RETUSP30 | |
| SCHEMBL19991694 | 0.82 | GPR119 (0.62) | GPR119RETUSP30 | |
| SCHEMBL27090945 | 0.82 | GPR119 (0.68) | GPR119 | |
| SCHEMBL31254491 | 0.81 | GPR119 (0.49) | GPR119RETUSP30 | |
| SCHEMBL22495526 | 0.81 | GPR119 (0.70) | GPR119GRM5GRM1 | |
| SCHEMBL22495527 | 0.81 | GPR119 (0.70) | GPR119GRM5GRM1 | |
| SCHEMBL29461508 | 0.81 | GPR119 (0.70) | GPR119GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233951-A1 | HETEROCYCLIC COMPOUNDS FOR IMAGING AGGREGATED ALPHA SYNUCLEIN IN THE SYNUCLEINOPATHIES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-11-14 | — | — | WO | disclosed |