Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | POLR1A | O95602 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31254496 | 0.81 | GPR119 (0.62) | GPR119RETUSP30 | |
| SCHEMBL31254485 | 0.80 | GPR119 (0.46) | GPR119RETUSP30PDE10A | |
| SCHEMBL20456684 | 0.79 | RET (0.52) | GPR119RETUSP30HDAC1 | |
| SCHEMBL30046919 | 0.79 | RET (0.52) | GPR119RETHDAC1SCN9A | |
| SCHEMBL31254501 | 0.79 | CKS1B (0.63) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL1480048 | 0.79 | CKS1B (0.63) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL17793695 | 0.76 | HRH3 (0.46) | GPR119RETUSP30 | |
| SCHEMBL21522470 | 0.76 | RET (0.50) | GPR119RET | |
| SCHEMBL31464957 | 0.76 | RET (0.50) | GPR119RET | |
| SCHEMBL27424943 | 0.76 | RET (0.50) | GPR119RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233951-A1 | HETEROCYCLIC COMPOUNDS FOR IMAGING AGGREGATED ALPHA SYNUCLEIN IN THE SYNUCLEINOPATHIES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-11-14 | — | — | WO | disclosed |