Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 6/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.41 |
| ▸ | LCK | P06239 | 3/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31254525 | 0.75 | RIPK2 (0.36) | RIPK2KDRTGFBR1LCKFASN | |
| SCHEMBL31043302 | 0.75 | RIPK2 (0.35) | RIPK2KDRTGFBR1LCKFASN | |
| SCHEMBL28048502 | 0.75 | ALDH1A1 (0.54) | RIPK2KDRTGFBR1LCKFASN | |
| SCHEMBL31390348 | 0.75 | RIPK2 (0.46) | RIPK2KDRTGFBR1LCKFASN | |
| SCHEMBL31254526 | 0.70 | FASN (0.42) | RIPK2KDRTGFBR1LCKFASN | |
| SCHEMBL2458585 | 0.68 | NISCH (0.46) | RIPK2KDRTGFBR1LCKEGFR | |
| SCHEMBL2462260 | 0.68 | RIPK2 (0.61) | RIPK2RIPK3 | |
| SCHEMBL25786944 | 0.68 | RIPK2 (0.38) | RIPK2KDRTGFBR1LCKFASN | |
| SCHEMBL31017216 | 0.68 | RIPK2 (0.38) | RIPK2KDRTGFBR1LCKFASN | |
| SCHEMBL29478085 | 0.67 | RIPK2 (0.60) | RIPK2KDRTGFBR1LCKFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772164-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-10-15 | — | — | CN | disclosed |