SCHEMBL29478085

SCHEMBL29478085

c1ccc(-c2ccc3scnc3c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK2 O43353 4/20 0.60
KDR P35968 2/20 0.60
TGFBR1 P36897 2/20 0.60
EGFR P00533 1/20 0.60
RIPK3 Q9Y572 1/20 0.57
ALDH1A1 P00352 1/20 0.55
HSD17B10 Q99714 1/20 0.55
PIK3CD O00329 1/20 0.50
FFAR1 O14842 1/20 0.49
AURKA O14965 1/20 0.46
FASN P49327 1/20 0.45
DYRK1A Q13627 1/20 0.45
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
MCL1 Q07820 3/20 0.42
PIK3CA P42336 1/20 0.42
PI4KA P42356 1/20 0.42
PI4KB Q9UBF8 1/20 0.42
PDE10A Q9Y233 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL927048 1.00 RIPK2 (0.60) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL28048502 0.90 ALDH1A1 (0.54) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL28215553 0.87 RIPK2 (0.50) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL10887857 0.85 RIPK2 (0.49) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL6032917 0.85 DYRK1A (0.62) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL13394464 0.83 DYRK1A (0.51) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL6650934 0.83 FFAR1 (0.48) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL1852870 0.83 FFAR1 (0.48) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL11719234 0.83 RIPK2 (0.47) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL13394458 0.82 MAP4K4 (0.49) RIPK2KDRTGFBR1EGFRRIPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
CN-110669026-B Fluorescent probe molecule for detecting nitrite and preparation method thereof 中国科学院新疆理化技术研究所 2022-04-01 CN disclosed
CN-110669026-B Fluorescent probe molecule for detecting nitrite and preparation method thereof 中国科学院新疆理化技术研究所 2022-04-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 RIPK2 2816/4885KDR 1868/4885TGFBR1 298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.