SCHEMBL31255481

SCHEMBL31255481

N#Cc1ccc(OC[C@@H]2CCCO2)c(F)c1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 1/20 0.43
TSHR P16473 1/20 0.41
HTR2A P28223 2/20 0.39
SLC6A4 P31645 2/20 0.39
SCN9A Q15858 1/20 0.39
ALOX5AP P20292 1/20 0.38
FEN1 P39748 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
PKM P14618 1/20 0.37
IKBKE Q14164 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23847921 1.00 EGLN2 (0.43) EGLN2TSHRHTR2ASLC6A4SCN9A
SCHEMBL23847922 1.00 EGLN2 (0.43) EGLN2TSHRHTR2ASLC6A4SCN9A
SCHEMBL23835410 0.81 XDH (0.40) HTR2AIKBKE
SCHEMBL12496453 0.77 MAPT (0.42) TSHRHTR2ASLC6A4SCN9AALOX5AP
SCHEMBL12496456 0.77 MAPT (0.42) TSHRHTR2ASLC6A4SCN9AALOX5AP
SCHEMBL23835255 0.77 L3MBTL1 (0.40) SCN9AMEN1KMT2AKDM4ENPC1
SCHEMBL23854599 0.77 IRAK4 (0.40)
SCHEMBL23848164 0.77 IRAK4 (0.40)
SCHEMBL1197051 0.76 PTGER1 (0.46) EGLN2TSHRSMN1; SMN2KDM4EALDH1A1
SCHEMBL5842652 0.74 EGLN2 (0.43) EGLN2TSHRHTR2ASLC6A4SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 WO disclosed