SCHEMBL31256795

C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)O)[C@@H](C)O

nearest known ligand 0.57

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	10/20	0.57

▸	OPRD1	P41143	10/20	0.57

▸	OPRK1	P41145	8/20	0.55

▸	GLP1R	P43220	7/20	0.53

▸	SCTR	P47872	1/20	0.53

▸	BACE1	P56817	1/20	0.49

▸	BACE2	Q9Y5Z0	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31258952	0.96	OPRD1 (0.57)	OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL31256793	0.94	OPRM1 (0.55)	OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30407947	0.94	OPRM1 (0.55)	OPRM1OPRD1OPRK1GLP1R
SCHEMBL30299020	0.93	GLP1R (0.58)	OPRM1OPRD1OPRK1GLP1R
SCHEMBL31030934	0.92	GLP1R (0.57)	OPRM1OPRD1OPRK1GLP1R
SCHEMBL29858785	0.92	OPRD1 (0.53)	OPRM1OPRD1OPRK1
SCHEMBL30918524	0.92	GLP1R (0.58)	OPRM1OPRD1OPRK1GLP1R
SCHEMBL30636778	0.92	GLP1R (0.55)	OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30368416	0.89	OPRM1 (0.56)	OPRM1OPRD1OPRK1GLP1R
SCHEMBL30080556	0.89	OPRM1 (0.61)	OPRM1OPRD1OPRK1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111825758-B	GLP-1 and GIP co-agonist compounds	上海翰森生物医药科技有限公司	2024-11-22	—	—	CN	disclosed