Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.46 |
| ▸ | LOX | P28300 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940184 | 1.00 | LOXL2 (0.46) | LOXL2LOXSMN1; SMN2HPGDNOS3 | |
| SCHEMBL13226976 | 0.84 | NOS3 (0.53) | LOXL2LOXSMN1; SMN2HPGDNOS3 | |
| SCHEMBL29975842 | 0.82 | LOXL2 (0.67) | LOXL2LOXNOS3NOS1NOS2 | |
| SCHEMBL17342 | 0.82 | LOXL2 (0.67) | LOXL2LOXNOS3NOS1NOS2 | |
| Bromide SCHEMBL13858041 | 0.81 | LOXL2 (0.65) | LOXL2LOXNOS3NOS1NOS2 | |
| SCHEMBL2940362 | 0.81 | RECQL (0.50) | LOXL2LOXNOS3NOS1NOS2 | |
| SCHEMBL134512 | 0.81 | LOXL2 (0.46) | LOXL2LOXSMN1; SMN2HPGDNOS3 | |
| SCHEMBL4933505 | 0.81 | LOXL2 (0.70) | LOXL2LOXNOS3NOS1NOS2 | |
| SCHEMBL15504978 | 0.80 | LOXL2 (0.46) | LOXL2LOXACACBCYP4F2CYP4A11 | |
| SCHEMBL28718096 | 0.79 | LOXL2 (0.49) | LOXL2LOXSMN1; SMN2HPGDNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119110800-A | Modulators of interferon gene stimulating factor (STING), compositions and methods | 健道生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |