SCHEMBL31256972

CC(C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	19/20	0.48

▸	CTSD	P07339	3/20	0.48

▸	BACE2	Q9Y5Z0	3/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31257083	0.93	BACE1 (0.43)	BACE1CTSDBACE2
SCHEMBL31257073	0.89	MAGI3 (0.44)	BACE1CTSDBACE2
SCHEMBL29805325	0.89	BACE1 (0.44)	BACE1CTSDBACE2
SCHEMBL31256965	0.88	BACE1 (0.48)	BACE1
SCHEMBL30554861	0.87	MAGI3 (0.44)	BACE1CTSD
SCHEMBL30640025	0.87	BACE1 (0.48)	BACE1CTSDBACE2
SCHEMBL29630656	0.87	DPP4 (0.35)	BACE1
SCHEMBL30476106	0.86	BACE1 (0.49)	BACE1CTSDBACE2
SCHEMBL29630385	0.86	BACE1 (0.39)	BACE1CTSDBACE2
SCHEMBL29683498	0.85	BACE1 (0.40)	BACE1CTSDBACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed