SCHEMBL31257083

CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	11/20	0.43

▸	CTSD	P07339	1/20	0.43

▸	GRPR	P30550	3/20	0.41

▸	BACE2	Q9Y5Z0	2/20	0.39

▸	GLP1R	P43220	2/20	0.39

▸	SCTR	P47872	1/20	0.39

▸	MAGI3	Q5TCQ9	1/20	0.39

▸	ERBB2	P04626	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31257073	0.94	MAGI3 (0.44)	BACE1CTSDGRPRBACE2GLP1R
SCHEMBL31256972	0.93	BACE1 (0.48)	BACE1CTSDBACE2
SCHEMBL29805325	0.92	BACE1 (0.44)	BACE1CTSDBACE2GLP1RSCTR
SCHEMBL31041712	0.89	CRHR1 (0.39)	GRPRGLP1RSCTRMAGI3
SCHEMBL31041723	0.88	BACE1 (0.47)	BACE1CTSDGRPRGLP1RSCTR
SCHEMBL31041728	0.88	BACE1 (0.49)	BACE1CTSDGRPRGLP1RSCTR
SCHEMBL31257072	0.87	MAGI3 (0.48)	BACE1GLP1RMAGI3
SCHEMBL31041711	0.86	CALCR (0.42)	GLP1RSCTR
SCHEMBL31257065	0.86	MAGI3 (0.42)	BACE1CTSDGRPRBACE2GLP1R
SCHEMBL32677403	0.85	BACE1 (0.45)	BACE1CTSDBACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed