SCHEMBL31256965

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	2/20	0.48

▸	CCNA2	P20248	2/20	0.43

▸	CDK2	P24941	2/20	0.43

▸	CCNA1	P78396	2/20	0.43

▸	GLP1R	P43220	7/20	0.43

▸	CALCR	P30988	4/20	0.42

▸	CRHR1	P34998	1/20	0.42

▸	CRHR2	Q13324	1/20	0.42

▸	VIPR1	P32241	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10619527	0.97	BACE1 (0.48)	BACE1CCNA2CDK2CCNA1GLP1R
SCHEMBL10619539	0.97	BACE1 (0.48)	BACE1CCNA2CDK2CCNA1GLP1R
SCHEMBL30338373	0.89	BACE1 (0.46)	BACE1GLP1RCALCRCRHR1CRHR2
SCHEMBL30293834	0.89	NTSR2 (0.45)	BACE1CCNA2CDK2CCNA1
SCHEMBL31256972	0.88	BACE1 (0.48)	BACE1
SCHEMBL29994497	0.87	BACE1 (0.48)	BACE1GLP1RVIPR1
SCHEMBL14921120	0.86	VIPR2 (0.44)	CCNA2CDK2CCNA1GLP1RVIPR1
SCHEMBL31180771	0.86	NTSR2 (0.46)	BACE1CCNA2CDK2CCNA1
SCHEMBL31041712	0.85	CRHR1 (0.39)	CCNA2CDK2CCNA1GLP1RCALCR
SCHEMBL30554861	0.85	MAGI3 (0.44)	BACE1GLP1RCRHR1CRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed