SCHEMBL31257013

CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	12/20	0.59

▸	OPRM1	P35372	10/20	0.59

▸	OPRK1	P41145	2/20	0.56

▸	OPRL1	P41146	3/20	0.49

▸	TFPI	P10646	1/20	0.49

▸	CD40	P25942	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31256995	0.96	OPRD1 (0.57)	OPRD1OPRM1OPRK1TFPICD40
SCHEMBL31257019	0.94	OPRD1 (0.57)	OPRD1OPRM1OPRK1OPRL1
SCHEMBL29549877	0.93	OPRD1 (0.59)	OPRD1OPRM1OPRK1TFPICD40
SCHEMBL31257052	0.91	OPRM1 (0.58)	OPRD1OPRM1OPRK1TFPICD40
SCHEMBL31257082	0.90	OPRD1 (0.56)	OPRD1OPRM1OPRK1CD40
SCHEMBL31257045	0.89	OPRM1 (0.56)	OPRD1OPRM1OPRK1OPRL1
SCHEMBL31256946	0.89	OPRD1 (0.60)	OPRD1OPRM1OPRK1
SCHEMBL31257081	0.88	OPRD1 (0.64)	OPRD1OPRM1OPRK1
SCHEMBL31257077	0.87	OPRM1 (0.57)	OPRD1OPRM1OPRK1OPRL1
SCHEMBL31243872	0.86	OPRD1 (0.64)	OPRD1OPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed