Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861953 | 0.90 | OPRM1 (0.43) | PTGS1GSTK1CTSBOPRM1OPRD1 | |
| SCHEMBL10861943 | 0.90 | OPRM1 (0.43) | PTGS1GSTK1CTSBOPRM1OPRD1 | |
| SCHEMBL30051701 | 0.90 | ALDH1A1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL30051918 | 0.88 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTLAP3CTSB | |
| SCHEMBL30661453 | 0.87 | PTGS1 (0.47) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL30661454 | 0.87 | PTGS1 (0.47) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL31036849 | 0.87 | PTGS1 (0.44) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL31461857 | 0.84 | PTGS1 (0.45) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL31111445 | 0.84 | ALDH1A1 (0.41) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL30569782 | 0.82 | PSMB5 (0.54) | PTGS1GSTK1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240352445-A1 | HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES | ABWIZ BIO, INC. | 2024-10-24 | — | — | US | disclosed |