SCHEMBL31257067

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	10/20	0.47

▸	ENPEP	Q07075	5/20	0.44

▸	CTSD	P07339	4/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31257006	0.96	ENPEP (0.46)	BACE1ENPEPCTSD
SCHEMBL31257088	0.90	BACE1 (0.48)	BACE1ENPEPCTSD
SCHEMBL31257036	0.90	BACE1 (0.47)	BACE1CTSD
SCHEMBL30658566	0.87	ENPEP (0.48)	BACE1ENPEP
SCHEMBL30561566	0.86	BACE1 (0.47)	BACE1CTSD
SCHEMBL31257011	0.86	BACE1 (0.45)	BACE1
SCHEMBL31256970	0.86	BACE1 (0.46)	BACE1
SCHEMBL30259430	0.85	BACE1 (0.47)	BACE1CTSD
SCHEMBL30031957	0.85	BACE1 (0.47)	BACE1CTSD
SCHEMBL31234146	0.85	BACE1 (0.51)	BACE1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed