SCHEMBL31256970

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C(C)C)[C@@H](C)O

nearest known ligand 0.51

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	1/20	0.46

▸	OPRL1	P41146	2/20	0.40

▸	GLP1R	P43220	2/20	0.39

▸	OPRM1	P35372	2/20	0.39

▸	OPRD1	P41143	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31257036	0.96	BACE1 (0.47)	BACE1
SCHEMBL31257011	0.92	BACE1 (0.45)	BACE1OPRL1OPRM1OPRD1
SCHEMBL30567745	0.86	BACE1 (0.47)	BACE1GLP1R
SCHEMBL31257067	0.86	BACE1 (0.47)	BACE1
SCHEMBL31257019	0.85	OPRD1 (0.57)	BACE1OPRL1GLP1ROPRM1OPRD1
SCHEMBL31257013	0.84	OPRD1 (0.59)	OPRL1OPRM1OPRD1
SCHEMBL30974555	0.84	BACE1 (0.44)	BACE1
SCHEMBL32679433	0.83	DPP8 (0.41)	—
SCHEMBL30518992	0.82	RXFP1 (0.46)	OPRL1
SCHEMBL31257006	0.82	ENPEP (0.46)	BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed