Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | GRB2 | P62993 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31257078 | 0.93 | OPRD1 (0.52) | OPRD1OPRM1OPRK1MMEACE | |
| SCHEMBL29448580 | 0.88 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31648346 | 0.87 | OPRD1 (0.60) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29364824 | 0.86 | OPRD1 (0.61) | OPRD1OPRM1OPRK1ACE | |
| SCHEMBL29448576 | 0.85 | OPRD1 (0.55) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31256976 | 0.84 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 | |
| SCHEMBL32665682 | 0.84 | CTSD (0.51) | OPRD1OPRM1OPRK1MMEACE | |
| SCHEMBL29448571 | 0.83 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31257076 | 0.83 | OPRD1 (0.54) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29472198 | 0.83 | OPRD1 (0.58) | OPRD1OPRM1OPRK1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240352445-A1 | HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES | ABWIZ BIO, INC. | 2024-10-24 | — | — | US | disclosed |