Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 4/20 | 0.47 |
| ▸ | CCND1 | P24385 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6084950 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL28261607 | 0.85 | KCNA3 (0.53) | HTTSMN1; SMN2LMNAPLAUHTR6 | |
| SCHEMBL31258085 | 0.85 | PPARG (0.56) | HTR6CDK4CCND1KDM4EPPARG | |
| SCHEMBL6087034 | 0.85 | PPARG (0.56) | HTR6CDK4CCND1KDM4EPPARG | |
| SCHEMBL31258040 | 0.82 | CDK4 (0.49) | PLAUHTR6CDK4CCND1KMT2A | |
| SCHEMBL6087030 | 0.82 | CDK4 (0.49) | PLAUHTR6CDK4CCND1KMT2A | |
| SCHEMBL31257954 | 0.81 | HTR6 (0.56) | SMN1; SMN2LMNAPLAUHTR6CDK4 | |
| SCHEMBL6087404 | 0.81 | HTR6 (0.56) | SMN1; SMN2LMNAPLAUHTR6CDK4 | |
| SCHEMBL6086852 | 0.80 | CDK4 (0.45) | HTR6CDK4CCND1PPARG | |
| SCHEMBL6085492 | 0.79 | CDK4 (0.47) | PLAUHTR6CDK4CCND1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080667-A | Aminoguanidine indole derivative and preparation method and application thereof | 中国农业科学院兰州畜牧与兽药研究所 | 2024-12-06 | — | — | CN | claimed |
| CN-119080667-A | Aminoguanidine indole derivative and preparation method and application thereof | 中国农业科学院兰州畜牧与兽药研究所 | 2024-12-06 | — | — | CN | disclosed |