SCHEMBL31258247

SCHEMBL31258247

O=C(O)c1cccc(Br)c1Cc1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.46
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2C19 P33261 2/20 0.40
MIF P14174 1/20 0.40
CYP2C9 P11712 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GRIK1 P39086 1/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
PRNP P04156 1/20 0.40
BRS3 P32247 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
HTT P42858 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4844133 0.83 TSHR (0.53) NR4A1LMNAMAPTTSHRALDH1A1
Hydrochloric Acid SCHEMBL28047976 0.75 PRNP (0.45) NR4A1TSHRALDH1A1HPGDPRNP
SCHEMBL31347194 0.74 PRNP (0.47) NR4A1MAPTTSHRALDH1A1HPGD
SCHEMBL625115 0.74 PRNP (0.47) NR4A1MAPTTSHRALDH1A1HPGD
SCHEMBL29836943 0.74 PRNP (0.47) NR4A1MAPTTSHRALDH1A1HPGD
SCHEMBL2727816 0.74 PRNP (0.47) NR4A1MAPTTSHRALDH1A1HPGD
SCHEMBL27976300 0.74 AKR1C3 (0.47) MAPTALDH1A1L3MBTL1HPGDPRNP
SCHEMBL27488099 0.74 ALDH1A1 (0.54) NR4A1TSHRALDH1A1HPGDNR4A2
SCHEMBL5455144 0.73 ALDH1A1 (0.57) NR4A1LMNAMAPTTSHRALDH1A1
SCHEMBL1964828 0.73 HPGD (0.40) LMNAMAPTTSHRCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039526-A Special polycarboxylate water reducer for desert sand concrete, preparation method of polycarboxylate water reducer and desert sand concrete 科之杰新材料集团有限公司 2024-11-29 CN disclosed