Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25168462 | 1.00 | LTB4R (0.45) | LTB4RKDM4EGAANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL25175077 | 0.99 | LTB4R (0.44) | LTB4RKDM4EGAANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL31220087 | 0.99 | LTB4R (0.44) | LTB4RKDM4EGAANPSR1RXFP1 | |
| SCHEMBL31258613 | 0.89 | RAB9A (0.36) | LTB4RKDM4EPRMT5MAPTALDH1A1 | |
| SCHEMBL25168395 | 0.89 | RAB9A (0.36) | LTB4RKDM4EPRMT5MAPTALDH1A1 | |
| SCHEMBL25167934 | 0.88 | TLR8 (0.36) | LTB4RKDM4EGAAPRMT5HPGD | |
| SCHEMBL31258624 | 0.88 | TLR8 (0.36) | LTB4RKDM4EGAAPRMT5HPGD | |
| SCHEMBL25171841 | 0.87 | TSHR (0.40) | KDM4EGAABACE1MAPTHPGD | |
| SCHEMBL31258625 | 0.87 | TSHR (0.40) | KDM4EGAABACE1MAPTHPGD | |
| SCHEMBL25168423 | 0.84 | MAPT (0.41) | KDM4EGAARXFP1BACE1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974035-A | 2-Aminoimidazole derivatives as PRMT5 inhibitors | 米拉蒂医疗股份有限公司 | 2024-11-15 | — | — | CN | claimed |