Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904502 | 0.76 | CYP1A2 (0.60) | OPRM1MEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL22122308 | 0.75 | OPRM1 (0.59) | OPRM1ALDH1A1CHRM1DRD2PLD2 | |
| SCHEMBL7248358 | 0.75 | HPGD (0.74) | MAPK9EPHX2PPARGHPGDOPRM1 | |
| SCHEMBL2321983 | 0.75 | LMNA (0.53) | OPRM1ALDH1A1KMT2ACHRM1PLD2 | |
| SCHEMBL5278517 | 0.74 | MAPK9 (0.51) | MAPK9EPHX2PPARGHPGDOPRM1 | |
| SCHEMBL5241130 | 0.74 | MAPK9 (0.67) | MAPK9EPHX2PPARGHPGDOPRM1 | |
| SCHEMBL5242145 | 0.74 | MAPK9 (0.51) | MAPK9EPHX2PPARGHPGDOPRM1 | |
| SCHEMBL739521 | 0.73 | HPGD (0.62) | HPGDOPRM1MEN1ALDH1A1CYP3A4 | |
| SCHEMBL5241797 | 0.73 | MAPK9 (0.66) | MAPK9EPHX2PPARGHPGDOPRM1 | |
| SCHEMBL2949618 | 0.73 | MTOR (0.55) | MAPK9EPHX2PPARGHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060045-A | Thiazole urea derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |